Biomcp server
MCP bio bridgeFrom its SKILL.md
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SKILL.md
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BioMCP Server
Deploy and operate the BioMCP server so MCP-compatible clients (Claude Desktop, LobeChat, etc.) can query biomedical databases via a single standardized interface.
When to Use
- Unified literature search (PubMed/PMC) inside MCP clients.
- Entity normalization via PubTator3 or genomic variant lookups.
- ClinicalTrials.gov queries without bespoke API wrappers.
Core Capabilities
- PubMed/PMC search: Execute complex literature queries.
- PubTator3 annotations: Map text to genes, diseases, chemicals, species.
- ClinicalTrials.gov: Retrieve trial metadata/protocols.
- Genomic variant lookups: Fetch variant/gene summaries from connected sources.
Deployment Workflow
- Install deps:
cd repo && uv sync(preferred) orpip install .. - Run server:
python -m biomcp.serverormake run; Docker Compose provided. - Configure client: Add command/args snippet from
README.mdinto MCP client config (Claude Desktop, BioKernel, etc.). - Test tools: Invoke PubMed + ClinicalTrials + variant endpoints to ensure connectivity.
- Monitor: Capture logs, rate-limit statuses, and data-source versions for audit.
Guardrails
- Keep API keys/env secrets outside the repo.
- Respect upstream rate limits to avoid throttling or bans.
- Document which data sources are enabled per deployment and update when they change.
References
- Source repo + configuration examples in
README.md,repo/docker-compose.yml, andrepo/Makefile.
What ships with it: 338 files
8704.9 KB alongside SKILL.md, 216 of them executable
repo/
- BIOMCP_DATA_FLOW.md7.8 KB
- CHANGELOG.md15.2 KB
- CNAME11 B
- codecov.yaml138 B
- docker-compose.yml384 B
- Dockerfile1.0 KB
- docs/apis/error-codes.md13.5 KB
- docs/apis/overview.md3.5 KB
- docs/apis/python-sdk.md12.8 KB
- docs/assets/biomcp-cursor-locations.png161.6 KB
- docs/assets/favicon.ico32.5 KB
- docs/assets/icon.png88.4 KB
- docs/assets/logo.png147.2 KB
- docs/assets/mcp_architecture.txt1.7 KB
- docs/assets/remote-connection/00_connectors.png176.9 KB
- docs/assets/remote-connection/01_add_custom_connector.png211.5 KB
- docs/assets/remote-connection/02_connector_enabled.png36.1 KB
- docs/assets/remote-connection/03_connect_to_biomcp.png45.9 KB
- docs/assets/remote-connection/04_select_google_oauth.png41.9 KB
- docs/assets/remote-connection/05_success_connect.png186.3 KB
- docs/backend-services-reference/01-overview.md5.7 KB
- docs/backend-services-reference/02-biothings-suite.md10.7 KB
- docs/backend-services-reference/03-cbioportal.md4.8 KB
- docs/backend-services-reference/04-clinicaltrials-gov.md6.6 KB
- docs/backend-services-reference/05-nci-cts-api.md10.0 KB
- docs/backend-services-reference/06-pubtator3.md6.6 KB
- docs/backend-services-reference/07-alphagenome.md12.3 KB
- docs/blog/ai-assisted-clinical-trial-search-analysis.md4.3 KB
- docs/blog/images/deep-researcher-video.png420.2 KB
- docs/blog/images/researcher-announce.png1225.3 KB
- docs/blog/images/researcher-drop-down.png112.2 KB
- docs/blog/images/researcher-prompt.png290.9 KB
- docs/blog/images/trial-search-assistant.png233.3 KB
- docs/blog/images/what_is_biomcp_thumbnail.png1103.8 KB
- docs/blog/researcher-persona-resource.md6.9 KB
- docs/changelog.md13.3 KB
- docs/CNAME11 B
- docs/concepts/01-what-is-biomcp.md3.3 KB
- bio_mcp_server.pyruns2.7 KB
- README.md1.2 KB
298 more files not listed here. See all 338 in the repository.