agentsclimarketplace

Uspto database

Skill BioTender-max/awesome-bio-agent-skills/skills/sciagent/uspto-database

A curated collection of AI agent skills for biomedical research, covering genomics, proteomics, single-cell analysis, clinical AI, and protein design.

Install
npx -y skills add BioTender-max/awesome-bio-agent-skills --skill uspto-database

Assembled from the repository path, not quoted from the project. Check it against their README if it does not work.

One thing to look at

  • no licenseNo license file was found in the repository. Code published without one is not open source by default, so using it at work is a question for whoever answers licensing questions where you are.

What its author says it does

Copied from the file, not written here

Access USPTO patent data via PatentsView REST API and Google Patents Public Data (BigQuery). Search by inventor, assignee, CPC, or keywords; download metadata and claims; analyze portfolios; track tech trends. For IP landscape analysis, competitor monitoring, prior art search, and tech forecasting in life sciences and biotech.

The file declares its own license as CC0-1.0. That is the author’s claim about this one file, and it is not the same thing as the license GitHub reports for the repository, which is listed with the other numbers below.

SKILL.md

18.0 KB, as published. Nobody here has run it

uspto-database

Overview

The USPTO provides two primary programmatic access points for patent data: the PatentsView API (REST, free, no key required for basic use) for structured queries by inventor, assignee, CPC classification, and keywords; and Google Patents Public Data (BigQuery public dataset) for large-scale analytics across the full patent corpus. Both expose data under the CC0 Public Domain Dedication. This skill covers Python-based access patterns for both, plus basic patent portfolio analytics.

When to Use

  • Prior art search: Finding existing patents relevant to a technology before filing or to assess freedom-to-operate.
  • Competitor IP landscape analysis: Querying all patents from a specific assignee (company or institution) to map their technology portfolio.
  • CPC classification search: Finding patents in a specific technology area using Cooperative Patent Classification codes (e.g., C12N for nucleotides/genetic engineering).
  • Inventor network analysis: Identifying prolific inventors in a field and their institutional affiliations.
  • Technology trend tracking: Counting patent filings by year and technology category to identify emerging areas.
  • Life sciences IP analysis: Searching biotech-specific classifications (A61K for pharmaceuticals, C12N for genetics, G16B for bioinformatics).
  • For full-text patent PDF downloads, use the USPTO Bulk Data Storage System (BDSS) or Google Patents direct links.
  • Rate limits: PatentsView API allows 45 requests/minute without an API key; request a free key for 45 req/min with higher daily limits.

Prerequisites

  • Python packages: requests, pandas, matplotlib
  • Optional: google-cloud-bigquery for Google Patents Public Data queries
  • Data requirements: No account needed for PatentsView basic queries; Google Cloud account required for BigQuery
  • Rate limits: PatentsView — 45 requests/minute (unauthenticated), higher with free API key
pip install requests pandas matplotlib
pip install google-cloud-bigquery  # optional: for BigQuery access

Quick Start

import requests
import pandas as pd

# Search PatentsView API: patents assigned to "Genentech" in CPC class C12N
url = "https://api.patentsview.org/patents/query"
payload = {
    "q": {"_and": [
        {"_contains": {"assignee_organization": "Genentech"}},
        {"_contains": {"cpc_subgroup_id": "C12N"}},
    ]},
    "f": ["patent_number", "patent_title", "patent_date", "assignee_organization"],
    "o": {"per_page": 25},
}
resp = requests.post(url, json=payload)
data = resp.json()
df   = pd.DataFrame(data["patents"])
print(f"Found: {data['total_patent_count']} patents")
print(df[["patent_number", "patent_title", "patent_date"]].head())

Core API

Query Type 1: Search by Assignee (Company / Institution)

Find all patents granted to a specific organization.

import requests
import pandas as pd

def search_by_assignee(assignee_name: str, per_page: int = 100) -> pd.DataFrame:
    url     = "https://api.patentsview.org/patents/query"
    payload = {
        "q": {"_contains": {"assignee_organization": assignee_name}},
        "f": [
            "patent_number", "patent_title", "patent_date",
            "patent_abstract", "assignee_organization", "assignee_country",
        ],
        "o": {"per_page": per_page, "sort": [{"patent_date": "desc"}]},
    }
    resp = requests.post(url, json=payload)
    resp.raise_for_status()
    data = resp.json()
    df   = pd.DataFrame(data.get("patents", []))
    print(f"Assignee '{assignee_name}': {data.get('total_patent_count', 0)} total patents")
    return df

# Example: patents from Broad Institute
df_broad = search_by_assignee("Broad Institute")
print(df_broad[["patent_number", "patent_title", "patent_date"]].head(10))
# Paginate through all results for large portfolios
def search_assignee_all_pages(assignee_name: str, page_size: int = 100) -> pd.DataFrame:
    url  = "https://api.patentsview.org/patents/query"
    all_patents = []
    page = 1
    while True:
        payload = {
            "q": {"_contains": {"assignee_organization": assignee_name}},
            "f": ["patent_number", "patent_title", "patent_date", "cpc_subgroup_id"],
            "o": {"per_page": page_size, "page": page},
        }
        resp = requests.post(url, json=payload)
        data = resp.json()
        patents = data.get("patents", [])
        if not patents:
            break
        all_patents.extend(patents)
        total = data.get("total_patent_count", 0)
        if len(all_patents) >= total:
            break
        page += 1

    df = pd.DataFrame(all_patents)
    print(f"Retrieved {len(df)} patents for '{assignee_name}'")
    return df

Query Type 2: Search by CPC Classification

CPC (Cooperative Patent Classification) codes organize patents by technology. Life sciences codes include C12N (nucleotides/genetics), A61K (pharmaceuticals), and G16B (bioinformatics).

import requests
import pandas as pd

# Search by CPC subgroup: C12N15 (mutation/genetic engineering)
url = "https://api.patentsview.org/patents/query"
payload = {
    "q": {"_begins": {"cpc_subgroup_id": "C12N15"}},
    "f": [
        "patent_number", "patent_title", "patent_date",
        "assignee_organization", "cpc_subgroup_id",
    ],
    "o": {"per_page": 50, "sort": [{"patent_date": "desc"}]},
}
resp = requests.post(url, json=payload)
data = resp.json()
df   = pd.DataFrame(data["patents"])
print(f"C12N15 patents: {data['total_patent_count']}")
print(df[["patent_number", "patent_title", "assignee_organization"]].head(10))
# Common life sciences CPC codes
CPC_LIFE_SCIENCES = {
    "C12N":    "Microorganisms / enzymes / compositions",
    "C12N15":  "Mutation / genetic engineering",
    "C12Q":    "Measuring / testing involving enzymes or microorganisms",
    "A61K":    "Preparations for medical use",
    "A61P":    "Therapeutic activity of chemical compounds",
    "G16B":    "Bioinformatics",
    "G16H":    "Healthcare informatics",
    "C07K":    "Peptides / proteins",
}
for code, desc in CPC_LIFE_SCIENCES.items():
    print(f"  {code:10s}: {desc}")

Query Type 3: Full-Text Keyword Search

Search patent titles and abstracts for specific terms.

import requests
import pandas as pd

def keyword_search(keyword: str, per_page: int = 50) -> pd.DataFrame:
    url = "https://api.patentsview.org/patents/query"
    payload = {
        "q": {"_or": [
            {"_text_any": {"patent_title":    keyword}},
            {"_text_any": {"patent_abstract": keyword}},
        ]},
        "f": [
            "patent_number", "patent_title", "patent_date",
            "patent_abstract", "assignee_organization",
        ],
        "o": {"per_page": per_page, "sort": [{"patent_date": "desc"}]},
    }
    resp = requests.post(url, json=payload)
    resp.raise_for_status()
    data = resp.json()
    df   = pd.DataFrame(data.get("patents", []))
    print(f"Keyword '{keyword}': {data.get('total_patent_count', 0)} patents found")
    return df

# Search for CRISPR-related patents
df_crispr = keyword_search("CRISPR")
print(df_crispr[["patent_number", "patent_title", "patent_date"]].head(10))

Query Type 4: Inventor Search

Find patents by inventor name or retrieve an inventor's full publication history.

import requests
import pandas as pd

# Search by inventor name
url = "https://api.patentsview.org/inventors/query"
payload = {
    "q": {"_and": [
        {"inventor_last_name":  "Doudna"},
        {"inventor_first_name": "Jennifer"},
    ]},
    "f": ["inventor_id", "inventor_first_name", "inventor_last_name",
          "inventor_city", "inventor_state", "inventor_country"],
    "o": {"per_page": 10},
}
resp = requests.post(url, json=payload)
data = resp.json()
print(f"Found {data.get('total_inventor_count', 0)} inventors matching 'Jennifer Doudna'")
for inv in data.get("inventors", []):
    print(f"  ID: {inv['inventor_id']}, Location: {inv.get('inventor_city')}, {inv.get('inventor_country')}")
# Get all patents for a specific inventor by inventor_id
inventor_id = "fl:j_ln:doudna-1"   # PatentsView inventor ID format

url = "https://api.patentsview.org/patents/query"
payload = {
    "q": {"inventor_id": inventor_id},
    "f": ["patent_number", "patent_title", "patent_date", "assignee_organization"],
    "o": {"per_page": 100, "sort": [{"patent_date": "desc"}]},
}
resp  = requests.post(url, json=payload)
data  = resp.json()
df    = pd.DataFrame(data.get("patents", []))
print(f"Patents for inventor {inventor_id}: {data.get('total_patent_count', 0)}")
print(df.head(5))

Query Type 5: Date Range and Combined Filters

Combine multiple filters for targeted searches.

import requests
import pandas as pd

# Patents in gene therapy (CPC A61K48) filed 2020-2024 by a US assignee
url = "https://api.patentsview.org/patents/query"
payload = {
    "q": {"_and": [
        {"_begins":    {"cpc_subgroup_id": "A61K48"}},
        {"_gte":       {"patent_date": "2020-01-01"}},
        {"_lte":       {"patent_date": "2024-12-31"}},
        {"_eq":        {"assignee_country": "US"}},
    ]},
    "f": [
        "patent_number", "patent_title", "patent_date",
        "assignee_organization", "patent_num_claims",
    ],
    "o": {"per_page": 100, "sort": [{"patent_date": "desc"}]},
}
resp = requests.post(url, json=payload)
data = resp.json()
df   = pd.DataFrame(data.get("patents", []))
print(f"Gene therapy patents 2020-2024 (US assignee): {data.get('total_patent_count', 0)}")
print(df[["patent_number", "patent_title", "patent_date", "assignee_organization"]].head(10))

Query Type 6: Google Patents BigQuery

For large-scale corpus analytics, use the public Google Patents dataset in BigQuery.

from google.cloud import bigquery

client = bigquery.Client(project="YOUR_GCP_PROJECT")

# Count CRISPR patents by year (Google Patents public data)
query = """
SELECT
    EXTRACT(YEAR FROM filing_date) AS filing_year,
    COUNT(*)                        AS patent_count,
    COUNT(DISTINCT assignee)        AS unique_assignees
FROM `patents-public-data.patents.publications`
WHERE
    (LOWER(title_localized[SAFE_OFFSET(0)].text) LIKE '%crispr%'
     OR LOWER(abstract_localized[SAFE_OFFSET(0)].text) LIKE '%crispr%')
    AND filing_date >= '2010-01-01'
    AND country_code = 'US'
GROUP BY filing_year
ORDER BY filing_year
"""
df_bq = client.query(query).to_dataframe()
print(df_bq)
print(f"Peak year: {df_bq.loc[df_bq.patent_count.idxmax(), 'filing_year']} "
      f"({df_bq.patent_count.max()} patents)")

Key Parameters

ParameterModuleDefaultRange / OptionsEffect
per_pagePatentsView "o"25110000Results per API call
pagePatentsView "o"11–max pagesPage number for pagination
sortPatentsView "o"API defaultany field + "asc"/"desc"Sort order of results
"f" fieldsPatentsViewminimalany valid field listFields returned in response (controls payload size)
"_begins"query operatorfield + prefix stringPrefix match (e.g., CPC code prefix)
"_contains"query operatorfield + substringSubstring search (case-insensitive)
"_text_any"query operatorfield + keywordsFull-text search on title/abstract fields

Best Practices

  1. Request only the fields you need: The "f" (fields) parameter controls what is returned. Requesting patent_abstract for thousands of patents significantly increases payload size and latency.

  2. Always handle pagination for large result sets: PatentsView caps responses at 10,000 per page maximum. For queries returning >10,000 results, use date-range slicing or narrower CPC codes to split the query.

  3. Cache API responses to disk: PatentsView is rate-limited; if building a dataset iteratively, save responses to JSON/CSV after each API call.

    import json, pathlib
    cache = pathlib.Path("cache")
    cache.mkdir(exist_ok=True)
    cache_file = cache / "genentech_patents.json"
    if not cache_file.exists():
        resp = requests.post(url, json=payload)
        cache_file.write_text(resp.text)
    data = json.loads(cache_file.read_text())
    
  4. Use CPC codes for technology-specific searches, not just keywords: Keywords miss synonyms and foreign-language patents; CPC codes are assigned by patent examiners and are more systematic.

  5. Validate assignee names: Company names in patent records vary (e.g., "Genentech Inc.", "Genentech, Inc.", "GENENTECH INC"). Use _contains for fuzzy matching, then deduplicate in pandas.

Common Workflows

Workflow 1: Technology Landscape Analysis — Filing Trends by Year

Goal: Count patents filed in a CPC class by year and plot the trend.

import requests
import pandas as pd
import matplotlib.pyplot as plt
from collections import defaultdict

def count_patents_by_year(cpc_prefix: str, start_year: int = 2010) -> pd.DataFrame:
    url  = "https://api.patentsview.org/patents/query"
    counts = defaultdict(int)
    page   = 1
    while True:
        payload = {
            "q": {"_and": [
                {"_begins": {"cpc_subgroup_id": cpc_prefix}},
                {"_gte":    {"patent_date": f"{start_year}-01-01"}},
            ]},
            "f": ["patent_number", "patent_date"],
            "o": {"per_page": 10000, "page": page},
        }
        resp    = requests.post(url, json=payload)
        patents = resp.json().get("patents", [])
        if not patents:
            break
        for p in patents:
            year = p["patent_date"][:4]
            counts[year] += 1
        total = resp.json().get("total_patent_count", 0)
        if sum(counts.values()) >= total:
            break
        page += 1

    df = pd.DataFrame(sorted(counts.items()), columns=["year", "count"])
    return df

df_trend = count_patents_by_year("C12N15", start_year=2010)

fig, ax = plt.subplots(figsize=(8, 4))
ax.bar(df_trend["year"], df_trend["count"], color="steelblue", edgecolor="white")
ax.set_xlabel("Year")
ax.set_ylabel("Patents granted")
ax.set_title("US Patents: C12N15 (Genetic Engineering) by Year")
plt.xticks(rotation=45)
plt.tight_layout()
plt.savefig("cpc_trend.png", dpi=150)
print(f"Trend plotted: {df_trend['count'].sum()} total patents -> cpc_trend.png")

Workflow 2: Assignee Portfolio Comparison

Goal: Compare patent counts across multiple biotech companies in a target CPC class.

import requests
import pandas as pd
import matplotlib.pyplot as plt

def count_patents_by_assignee(assignees: list, cpc_prefix: str) -> pd.DataFrame:
    url     = "https://api.patentsview.org/patents/query"
    records = []
    for assignee in assignees:
        payload = {
            "q": {"_and": [
                {"_contains": {"assignee_organization": assignee}},
                {"_begins":   {"cpc_subgroup_id": cpc_prefix}},
            ]},
            "f": ["patent_number"],
            "o": {"per_page": 1},  # only need total count
        }
        resp  = requests.post(url, json=payload)
        total = resp.json().get("total_patent_count", 0)
        records.append({"assignee": assignee, "patent_count": total})
        print(f"  {assignee}: {total} patents")

    df = pd.DataFrame(records).sort_values("patent_count", ascending=True)
    return df

companies = ["Genentech", "Amgen", "Regeneron", "AstraZeneca", "Novartis"]
df_comp   = count_patents_by_assignee(companies, cpc_prefix="A61K")

fig, ax = plt.subplots(figsize=(7, 4))
ax.barh(df_comp["assignee"], df_comp["patent_count"], color="salmon")
ax.set_xlabel("Patent count (A61K)")
ax.set_title("Pharmaceutical Patents by Assignee (CPC A61K)")
plt.tight_layout()
plt.savefig("assignee_comparison.png", dpi=150)
print("Comparison chart saved -> assignee_comparison.png")

Expected Outputs

  • pd.DataFrame with patent records (columns depend on requested "f" fields)
  • cpc_trend.png — bar chart of patent counts by year
  • assignee_comparison.png — horizontal bar chart comparing companies
  • total_patent_count in API response gives the full corpus size for a query

Troubleshooting

ProblemCauseSolution
HTTPError 429 Too Many RequestsExceeded 45 req/min rate limitAdd time.sleep(1.5) between requests; request a free API key
Empty patents list in responseQuery too narrow or field name incorrectCheck field names in PatentsView API docs; test query in the web UI first
Results miss known patentsExact string matching on assignee nameUse _contains instead of _eq; check for name variants
KeyError: patent_dateField not requested in "f" listAdd "patent_date" to the "f" array
BigQuery auth errorGCP credentials not configuredRun gcloud auth application-default login or set GOOGLE_APPLICATION_CREDENTIALS
CPC prefix returns no resultsInvalid CPC code or typoVerify code at CPC classification browser

References

Keep looking

Skills are one crate of 328,083. Ordering is by how many stacks a row turns up in, so the top of any crate is what has actually been picked rather than what has the most stars.