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Svm

Skill BioTender-max/awesome-bio-agent-skills/skills/neuroclaw/svm

Use this model doc whenever the user wants to perform disease classification with SVM. This is a non-deep-learning supervised route focused on neuroimaging-based case-control prediction from ROI-wise or tabular features.From its SKILL.md

Install
npx -y skills add BioTender-max/awesome-bio-agent-skills --skill svm

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SVM Model Doc

Overview

SVM is a classical non-deep-learning method for neuroimaging-based disease classification.

  • Model family: non-deep-learning supervised classification method
  • Typical objectives:
    • classify patient vs control groups from neuroimaging features
    • build discriminative models from ROI features or tabular summaries
    • export predictive scores and evaluation metrics
  • Primary input: preprocessed fMRI / sMRI derived features, labels, optional covariates
  • Primary output: class predictions, decision scores, cross-validation metrics

In NeuroClaw, this document is model-level guidance for SVM-based disease classification workflows rather than deep learning phenotype prediction.

Upstream preparation should usually be delegated to:

  • fmri-skill for fMRI preprocessing and ROI / voxel feature preparation
  • smri-skill for structural feature extraction when disease classification uses sMRI
  • nilearn-tool for concrete SVM fitting on prepared feature tables

Research use only.


Quick Start

1) Prepare disease classification inputs

Expected inputs:

  • subject-level labels such as patient / control
  • preprocessed imaging features
  • optional covariates such as age, sex, site
  • optional train / validation / test split definition

If features are not ready, delegate preprocessing to fmri-skill or smri-skill first.

2) SVM route

Representative operations:

  • prepare ROI-wise or tabular neuroimaging features
  • standardize features within the training fold
  • fit linear or kernel SVM for disease classification
  • export predictions, decision scores, and performance metrics

Example execution route:

# delegated through claw-shell after features are prepared
python skills/nilearn-tool/scripts/svm_classifier_reference.py \
  --features path/to/features.csv \
  --labels path/to/labels.csv \
  --target diagnosis \
  --cv 5 \
  --output-dir run_models_output/svm

Input / Output Contract

Required inputs

  • subject-level labels for disease classification
  • feature table or ROI summary matrix

Optional inputs

  • confounds or covariates table
  • train / validation / test split file
  • hyperparameter settings such as kernel, C, or number of CV folds

Produced outputs

  • predicted labels and decision scores
  • cross-validation metrics such as accuracy, AUC, sensitivity, specificity
  • fitted model artifact or coefficient table

Recommended Delegation

  • imaging preprocessing and feature preparation -> fmri-skill and/or smri-skill
  • concrete implementation of SVM -> nilearn-tool
  • shell execution and logging -> claw-shell

No execution before explicit plan confirmation.


When to Use SVM

  • The user wants classical disease classification instead of a deep learning model.
  • The dataset size is moderate and model interpretability matters.
  • ROI-level features are already prepared and SVM is sufficient.
  • The task is case-control prediction, diagnosis support, or cross-validated disease discrimination.

Limitations and Notes

  • SVM performance depends strongly on feature engineering, scaling, and leakage-free cross-validation.
  • Site effects and confounds can dominate disease classification if not controlled properly.
  • Small sample sizes can lead to optimistic estimates unless split strategy is rigorously managed.

Reference

Created At: 2026-04-14 00:34 HKT Last Updated At: 2026-04-14 00:45 HKT Author: chengwang96

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