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Mageck crispr analyzer

Skill a5c-ai/babysitter/library/specializations/domains/science/bioinformatics/skills/mageck-crispr-analyzer

MAGeCK CRISPR screen analysis skill for gene essentiality scoringFrom its SKILL.md

Install
npx -y skills add a5c-ai/babysitter --skill mageck-crispr-analyzer

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SKILL.md

1.3 KB, 148 tokens by cl100k_base, as published. Nobody here has run it

MAGeCK CRISPR Analyzer Skill

Purpose

Provide MAGeCK CRISPR screen analysis for gene essentiality scoring.

Capabilities

  • Guide read counting
  • Normalization and QC
  • Gene-level analysis
  • Pathway enrichment
  • MLE model for complex designs
  • Visualization outputs

Usage Guidelines

  • Count guides accurately from sequencing data
  • Normalize counts appropriately
  • Calculate gene-level scores
  • Enrich for biological pathways
  • Use MLE for complex experimental designs
  • Generate informative visualizations

Dependencies

  • MAGeCK
  • BAGEL
  • CRISPResso2

Process Integration

  • CRISPR Screen Analysis (crispr-screen-analysis)

What ships with it

Read from the repository

Just SKILL.md. No reference files, no scripts.

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